Valentina Borzillo
Italy
Research Article
Radiosurgery and Stereotactic Radiotherapy for Brain Metastases
According the New Prognostic Indexes: our Preliminary Experience
Author(s): Valentina Borzillo, Francesca Maria Giugliano, Sara Falivene, Fabrizio Cammarota, Vincenzo Ravo, Paolo Muto and Rossella Di FrancoValentina Borzillo, Francesca Maria Giugliano, Sara Falivene, Fabrizio Cammarota, Vincenzo Ravo, Paolo Muto and Rossella Di Franco
Purpose: This work is a retrospective analysis of our experience in the treatment of patients with BMs using SRS or SRT with Cyberknife ® (CK) system (Accuray Inc., Sunnyvale, California, USA). The aim is to evaluate the local control of disease and overall survival according to modern prognostic indices. Material and methods: From November 2012 to March 2014, we treated 116 patients, (178 brain metastases), with CK system, an image-guided frameless robotic SRS/SRT. We stratified the patients according to the Diagnosis- Specific GPA (DS-GPA) and we treated patients with a single fraction (10-24 Gy) in 72%, with two fractions (18-21 Gy) in 3%, with three fractions (18-24 Gy) in 23%, with five fractions (20-25Gy) in 2%. The dose was prescribed to 80% isodose line. All patients were evaluated with clinical and radiologica.. View More»