Vittorio Emanuele Bianchi
V. Rovereta, 42, Falciano, San Marino
Italy
Research Article
Metabolic Syndrome, Obesity Paradox and Testosterone Level
Author(s): Vittorio Emanuele BianchiVittorio Emanuele Bianchi
Metabolic Syndrome (MetS) is a cluster of risk factors proposed as a prevalent responsible for the development of Atherosclerotic Cardiovascular Diseases (ACVD). The predominant risk factors are obesity, abdominal obesity and insulin resistance. People in middle age with MetS are at increased absolute risk for ACVD. Criticism for MetS include its imprecise in definition, its uncertain pathogenesis as a marker of ACVD risk, and questions regarding whether this ?cluster? of risk factors portend risk above and beyond the its individual components. Abdominal and visceral obesity evaluated by Waist-Circumferences (WC) and Waist-Hip-Ratio (WHR) are more specific than Body Mass Index (BMI) in definition of cardiovascular risk, but the triglycerides/HDL cholesterol ratio (TG/HDL-C) is adequate and better than MetS in diagnosis cardiovascular risk. However, evidence of an obesity paradox i.e. tha.. View More»
