Zaini A
Malaysia
Research Article
Rapid effects of novel phytoandrogen adjuvant therapy (PAT) on metabolic health: a gender, age and BMI matched case-control study
Author(s): Ong YC, Su LH and Zaini AOng YC, Su LH and Zaini A
Background and Aim: The human androgen receptor (AR) is a key nuclear transcription factor that controls expression of genes involved in anabolism - such as musculoskeletal remodelling and body fat mobilisation to ATP energy production – processes which directly impact aspects of metabolic health. This study evaluates the adjuvant effects of orally administered AR-modulating phytoandrogens and suprahormonal lipidic augmenters (SuHLAs) combined with an integrative weight-healthcare regimen of polyvalent pharmacotherapy (hypoglycemic, lipid modifying and anti-inflammatory) and mild lifestyle intervention, over intervals of 2-4 weeks.
Method: The total intention-to-treat (ITT) population consisted solely of women (N = 15) and were screened at baseline for metabolic health status, assessed via arterial blood pressure (BP), body fat (BF), lea.. View More»