Department of Biochemistry, Faculty of Life Sciences, University of Benin, Benin City, Nigeria
Research Article
Alpha amylase and alpha glucosidase inhibitory activities of isolated total saponins and tannins of Dialium guineense stem bark
Author(s): Abu Onoagbe* and Osemwenoyenmwen
Background: Dialium guineense belongs to the Leguminosae family,
and grows in dense forests in Africa along the southern edge of the
Sahel. The bark, leaves and fruits of the plant have medicinal properties
and are used to treat diseases such as stomatitis, toothache, fever,
diarrhoea, palpitations, and microbial infections.
Aim: The present study investigated the α-amylase and α-glucosidase
inhibitory activities of isolated total saponins and tannins of Dialium
guineense stem bark.
Methods: Total saponins and tannins were isolated from D. guineense
stem bark using standard method. Alpha amylase and alpha glucosidase
inhibitory activities of the extracts were determined in vitro. Acarbose
was used as the reference drug.
Results: The results showed that both extr.. View More»
