Hospital for Rehabilitation of Craniofacial Anomalies, University of São Paulo, Bauru, Brazil
Review Article
Dental Phenotypes in Van der Woude Syndrome: An Integrative Review
Author(s): Aline Cris tina da Silva Trevizan, Pollyana Pereira Teotonio dos Santos, Maria Carolina de Moraes Pereira and Lucimara Teixeira das Neves*
Introduction: Van der Woude Syndrome (VWS) consists of a genetic abnormality attributed to mutations in the IRF6 gene, characterized by the presence of paramedian pits in the lower lip, cleft lip and/or palate and hypodontia. Phenotypes of the syndrome are related to the oral cavity, and then other dental anomalies would also be present in this specific syndrome.
Objective: The aim of this study was to identify different dental phenotypes in subjects with VWS through an integrative review of the literature.
Materials and methods: A systematic search was conducted in Pubmed/Medline for articles which assessed dental phenotypes in van der Woude syndrome.
Results: Six publications were selected, considering the eligibility criteria of the articles. Different dental phenotypes are described i.. View More»
