Department of Pharmacy, BRAC University, Dhaka, Bangladesh
Research
Effect of Probiotics in the Treatment of Acute Watery Diarrhoea in Children Admitted to a Tertiary Care Hospital in Bangladesh: A Non-Randomized Prospective Clinical Trial
Author(s): Abu Syed Md. Mosaddek*, M. Rinat Rizvi, Rumi Akter, Md. Saiful Islam, Md. Nurul Hossain, Hrishik Iqbal, David Gazal, Md. Salequl Islam and Fatima Farhana
Objective: The study aimed to assess the efficacy of probiotics in the context of acute watery Diarrhoea and their effects on serum immunoglobulin in children.
Methods: Prospective clinical trial in children aged one month to 12 years hospitalized with acute watery Diarrhoea in Uttara Adhunik Medical College, and allocated to receive probiotics, antibiotics, or probiotics + antibiotics for 30 days in accordance with the standard treatment protocol of Diarrhoea. Clinical outcome measurements included duration of Diarrhoea and treatment adverse events. Stool culture and blood immunoglobulin were analyzed on days 0 and 30.
Results: 166 enrolled children were divided into three groups: Group A (probiotics), Group B (antibiotics) and Group C (probiotics + antibiotics) with 98 participants returning for a follow-up visit on day 30. All groups were comparable in their bas.. View More»
DOI:
10.35248/1840-4529.22.14.341
