Journal of Multiple Sclerosis

Professor of Neurogastroenterology, GI Physiology Unit, University College London Hospital NHS Foundation Trust, United Kingdom

Publications

• Research Article   
  Validation of the Monitoring Efficacy of Neurogenic Bowel Dysfunction Treatment on Response (MENTOR) Tool in Individuals with Multiple Sclerosis
  Author(s): Concetta Brugaletta, Valentina Pssananti, Humayra Dervin, Katherine Wickham, Klaus Krogh and Emmanuel A*
  
  Objective: Bowel dysfunction is highly prevalent in patients with Multiple Sclerosis (MS). A tool to help decision-making of neurogenic bowel dysfunction treatment in this population is needed. We present a project to validate in this population the MENTOR tool, a three-dimensional instrument comprised of the Neurogenic Bowel Dysfunction (NBD) score, special attention (‘alarm’) symptoms and patient satisfaction. Methods: 69 individuals with MS completed the MENTOR tool prior to outpatient review. An expert Health Care Professional (HCP) blinded to the MENTOR outcome assessed the participants and made an independent treatment decision. We compared the tool outcome and therapeutic recommendation with the HCP opinion. Results: In our patient cohort, the MENTOR has a specificity of 80%, accuracy of 70% and a sensitivity of 60% with a positive and negative predictive value of 6.. View More»
  DOI: DOI: 10.35248/2376-0389

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