Department of Cardiology, Basaksehir Cam and Sakura City Hospital, Istanbul, Turkey
Research Article
Potential Clinical Significance of CXADR on COVID-19
Author(s): Duygu Kirkik*, Fatih Hacimustafaoglu and Ersin Ibisoglu
Background/aim: Some viral infections cause myocarditis.
Since myocarditis and Coronavirus show similar symptoms
(such as chest pain), it is important to distinguish between
these two diseases, both in determining the treatment to be
applied and in preventing the disease. This study aims to
demonstrate the potential clinical significance of CXADR and ACE2 in COVID-19 using an in silico approach.
Materials and methods: In this study, STRING and
GENEMANIA databases were used to understand similarities
between CXADR gene and ACE2. KEGG pathway was used to
analysis of viral myocarditis. Exome variant server and
polyphen2 database were used to find probably damaging
SNPs on the CXADR gene and it was shown where the CXADR gene was expressed by UCSC Genome Br.. View More»
DOI:
10.4172/JMBI.23.5(1).03