Department of Neurology, Nanjing Medical University, Jiangsu, China
Mini Review
Pathogenesis of Post-COVID-19 Parkinsonism and Parkinson's Disease
Author(s): Jin Yong*
After Alzheimer's disease, Parkinson's disease (PD) is the most common neurological condition worldwide. The hallmarks of Parkinson's disease (PD) are misfolded alpha-synuclein aggregation and dopaminergic neuron degeneration in the substantia nigra pars compacta, along with both motor and non-motor symptoms. A post-infection parkinsonian phenotype's presence has been connected to several viruses. As a result of the emergence of the severe acute respiratory syndrome coronavirus-2 (SARSCoV-2) infection, the 2019 coronavirus disease (COVID-19), which initially manifested as novel pneumonia, has developed into a complex syndrome with a variety of clinical manifestations, including subtle and potentially long-lasting neurological sequelae. Exosomes are extracellular nanovesicles that play essential roles in intercellular communication in pathological situations. They carry.. View More»
DOI:
10.35248/2376 0389.22.9.09.465