Editorial office, Journal of Neurology & Neurophysiology, Brussels, Belgium
Short Communication
Super-Resolving Microscopy in the Study of the Brain
Author(s): Kene Adan*
Our understanding of the nervous system is fundamentally influenced by fluorescence imaging methods. With an unsurpassed precision level, the development of several super-resolution microscopy techniques and customized fluorescent probes allows for direct observation of the neuronal structure and protein groupings in cellular sub-compartments. Superresolving visualization techniques in neurons reveal a fresh understanding of the sub-synaptic structure and function, cytoskeletal composition, distribution, motility, and signalling of membrane proteins, as well as the relationship between neurons and glia. When studying disease pathophysiology using cutting-edge imaging techniques, well-defined molecular targets in autoimmune and neurodegenerative disease models serve as great beginning points... View More»
DOI:
10.35248/2471-268X.22.13.12.775
