Dr. Aftab Laboratories, Karachi, Pakistan
Research
The use of Mean Platelet Volume (MPV) in differentiating between hyper destructive versus hypo productive thrombocytopenia
Author(s): Muhammad Faisal Bashir, Sidra Ghazanfer, Faiz Ahmed Faiz, Sarah Rafi, Hasan Osman Mahmoodf and Khalid Aftab*
Objective: To establish the use of the mean platelet volume (MPV) as a tool in distinguishing between the hyper destructive versus hypo productive causes of thrombocytopenia.
Methods: This study was conducted at pathology department, Khawaja Muhammad Safdar Medical College, Sialkot (KMSMCS) from July 2020 to December 2020. Ethical approval was obtained from ethical committee of KMSMCS. 180 patients having platelet count less than 100x109/L were enrolled. Patients were categorized into two groups;
A. Patients having thrombocytopenia due to increase destruction of platelets.
B. Patients having thrombocytopenia due to reduced production of platelets.
Patients were selected from the CBC print generated by the automated haematology analyzer. Platelet count was manually verified by examining peripheral blood smear (PBS) on glass slides. MPV was record.. View More»
