Editorial office, European Journal of Clinical Oncology,, India
Mini Review
Exosomes Derived From Acute Myeloid Leukaemia (AML) Have a Key Role in the Development and Survival of Tumors
Author(s): Kyle Mary* and Chase Lisa
Acute Myeloid Leukemia (AML) is a quickly aggressive hematopoietic disorder that progress due to the accumulation and clonal expansion of immature myeloid cells. Despite the latest developments in AML treatment, repeated relapses and drug resistance remain one of the major challenges in treatment of leukemia. Currently, it is well known that the components of the tumor microenvironment such as cellular and noncellular elements play a critical function in treatment failures of AML; also they are most common cause of complications including suppression of hematopoiesis. Exosomes are membrane-bound Extracellular Vesicles (EVs) that transfer signaling molecules and have attracted a large amount of attention due to their important role in intercellular communication in health and disease. Exosomes transport their diverse payload of chemicals, inc.. View More»
DOI:
10.35248/clinical-oncology. 4(3).34-35