Physical Therapy, Department of Internal Medicine, Cairo University Hospitals, Giza, Egypt
Research
Effect of Exercises Training on Fatigue, Depression and Physical Activity in Patients with Systemic Lupus Erythematosus
Author(s): Manal K Youssef*
Background: Systemic Lupus Erythematosus (SLE) is an autoimmune disease associated with widespread inflammation
and tissue damage. It is more common and severe among Blacks, Hispanics, and Asians; with higher incidence in women.
While the goals of medical treatment are to prevent flares and reduce organ damage, up to 50% of patients perceive their
health to be suboptimal with unaddressed needs including fatigue and pain. Recent SLE treatment guidelines focus on
improving quality of life. Fatigue in SLE is associated with lower fitness levels, reduced exercise capacity, reduced muscle
strength, and greater disability when compared to sedentary healthy subjects.
Aim: To compare the effect of aerobic exercise versus stretching and strengthening exercise on fatigue and physical
activity in patients with SLE.
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