Editorial office, Journal of Neurology & Neurophysiology, Brussels, Belgium
Mini Review
SARS-Central CoV-2's Nervous System Targets and Routes
Author(s): Mili Horton*
Neurological symptoms and indications show the presence of targets other than the major lung consequences of the Coronavirus Disease 2019 (COVID-19) pandemic. The SARS-CoV-2 coronavirus, which is the cause of COVID-19, demonstrates neurotropism for both the central and peripheral nervous systems. The virus can access the central nervous system by a variety of infective mechanisms and pathways, some of which skip the blood-brain barrier and others that compromise its integrity. There can be no doubt that the membrane-bound metalloprotease ACE2 serves as the SARS-CoV-2 host-cell receptor, according to a number of studies. The cellular location of the ACE2 enzyme in many tissues, including the central nervous system, has been examined using histochemical investigations and more recently, transcriptomics of mRNA... View More»
DOI:
10.35248/2471-268X.22.13.11.604
