Editorial office, Journal of Neurology & Neurophysiology, Brussels, Belgium
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HIV Infection and Neurotoxicity Related to Drugs of Abuse
Author(s): Mohamed Irfan*
HIV, a neurotropic virus, immediately invades the brain following infection. HIV replicates in the brain in a modest number of astrocytes, microglia, and macrophages, inducing inflammatory and neurotoxic host responses. The term "Hiv-Associated Neurocognitive Diseases" refers to severe neurological illnesses brought on by HIV (HAND). The development of abnormally low levels of motor coordination, focus, and memory are hallmarks of HAND. From Asymptomatic Neurocognitive Impairment (ANI), Mild Neurocognitive Disorder (MND), to the most severe HIV-Associated Dementia (HAD), HAND has a variety of clinical manifestations. The primary cause of HAND and the most prevalent neurologic condition affecting the brain in those infected with HIV-1 is HIV-Encephalitis (HIVE). There are nine main genetic subtypes of HIV-1, which are divided into three groups (M, O, and N) and demonstrate wi.. View More»
DOI:
10.35248/2471-268X.22.13.6.584
