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Journal of Multiple Sclerosis

ISSN - 2376-0389
NLM - 101654564

Paul Otien

Department of Neuroscience, Central Clinical School, Monash University, Australia

Publications

  • Commentary   
    Brain Barrier: Knowns and Unknowns in Health and Disease
    Author(s): Riccardo Tizzoni, Paul Otien and Nathaniel Guarnaccia*

    The current study indicates lower Candida levels, possibly influenced by factors like geography, lifestyle, diet, or analytical methods. Saccharomyces may play a role in both maintaining a healthy mycobiome and contributing to certain diseases. This suggests a potential strain-specific effect or the broader mycobiome composition's impact on disease development. Further research into the relationship between Saccharomyces, Candida, and other microbiome components in multiple sclerosis is necessary. Investigating fungi's role in disease progression or prevention is crucial. This study provides initial evidence of fungal microbiome disturbance in multiple sclerosis patients, paving the way for future research using advanced sequencing methods and larger sample sizes. Integrating these approaches with mechanistic studies will be essential for understanding fungi's precise role.. View More»

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