Journal of Multiple Sclerosis

Department of Neuroscience, Meerut Institute of Medical Science, Meerut, India

Publications

• Mini Review   
  Teriflunomide for Elderly Patients with Benign MS and Cognitive Impairment: Balancing Brain Atrophy Reduction with Safety Considerations
  Author(s): Priya Kumari* and Shivani Tomar
  
  Introduction This study investigates Teriflunomide's potential to mitigate brain atrophy and its impact on cognitive function in MS patients. Method The study combines a case study and a cohort study. The case involves a 60-year-old woman with MS experiencing cognitive decline despite a stable EDSS score. The cohort consisted of 46 clinically stable Multiple Sclerosis (MS) patients who received teriflunomide treatment. Brain atrophy markers and cognitive function were evaluated. Results The case study patient showed signs of cognitive decline on the SDMT. The cohort study revealed teriflunomide treatment did not affect the corpus callosum index but resulted in a significant increase in third ventricle width, a potential indicator of brain atrophy. Conclusion.. View More»
  

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