Department of Oral and Maxillofacial Pathology, Krishnadevaraya College of Dental Sciencesss, Bangalore-562157, India
Mini Review
Sclerosing Polycystic Adenosis/Adenoma-Changing Paradigm: A Mini Review
Author(s): Reshma Venugopal*, Radhika Manoj Bavle, Sudhakara Muniswamappa and Soumya Makarla
Sclerosing polycystic adenosis or adenoma- the term is open for discussion.
The lesion is termed sclerosing polycystic adenosis-a pseudo neoplastic
reactive inflammatory process that appears similar to sclerosing adenosis of
the breast- in the recent WHO 2017 salivary gland tumour classification. It is
categorised under other epithelial lesions as sclerosing polycystic adenosis
and considers sclerosing polycystic adenoma as a synonym. The evidence
to state the lesion to be a neoplastic process rather than reactive is on the
rise and consideration should be given based on the degree of dysplasia
that it presents, 30% local recurrence rate and genetic alteration related to
PI3K pathway and PTEN, a tumour suppressor gene. The major portion of the
ductal proliferations retains the lobular architecture and is lined by a layer of
myoepithelial cells with rar.. View More»
DOI:
10.35248/2572-5130.21.s4.005-007
