Editorial Office, Journal of Internal Medicine, Belgium
Review
Autoimmune Disease-Related Molecular and Cellular Mechanisms
Author(s): Robert Wellington*
Several autoimmune illnesses are becoming more common in the United States, according to evidence. As a result, the expense of clinical management of autoimmune disorders to the public health is increasing. Both genetic and environmental variables play a role in the onset and course of autoimmune disorders. Autoantibodies can be caused by deficiencies in key proteins that are normally involved in maintaining the internal environment's checks and balances. Autoimmunity has been linked to structural anomalies or a decrease in normal levels of the pentraxins (serum amylase-P protein, acute phase proteins, complement, and C-reactive proteins). The quality and amount of subsequent immune responses are determined by the type of ligand/receptor interactions that promote physical recruitment of various signals within the cell. CD95, also known as Fas/Apo-1, and its ligand CD95L regulate l.. View More»
DOI:
10.35248/1840-4529.22.14.7.375
