Department of Orthopaedics, All India Institute of Medical Sciences, Raipur, Chhattisgarh, India
Research Article
Evaluation of Outcome of Intraarticular PRP Injection in Osteoarthritis Knee
Author(s): Buddhadeb Nayak*, Harshal S Sakale, Alok C Agrawal, Bikram K Kar, Sankalp Sharma and Shubham Bhardwaj
Introduction: Osteoarthritis (OA) represents a failure of the diarthrodial, synovial lined joints. It is a degenerative non-inflammatory joint disease. Osteoarthritis is the leading cause of chronic disability, affecting more than 80% of the human population above 55 years. It is due to an imbalance between the destructive and reparative processes involved in repairing and regenerating articular cartilage in the synovial joints. Many options for management of early OA knee are already established in previous literature. Autologous PRP injection in knee joint is an early method of management of early OA knee. The Supra-physiological release of platelet-derived growth factors directly at the site of diseased cartilage may stimulate the natural regenerative signaling cascade and enhance the healing of tissue with further mediation of the anti-
inflammatory response. W.. View More»
