Salah Boudjadi, MD, PhD
Editor-in-Chief
Doctor, Molecular Pathology Section
National Cancer Institute, Center for Cancer Research, Bethesda, USA
Postdoctoral Scientist and Research Fellow
1. Currently, I am pursuing a research training to build on my previous expertise on the transcriptional control of gene expression in cancer diseases. Since I joined the Molecular Pathology Section lab in 2016, I have worked on developing conceptual and technical training skills in cell model engineering and the expression profiling analysis using bioinformatic tools. In addition, I participate frequently in different activities including grant writing, public speaking, mentoring students, and teaching workshops. My research work is providing new data on the involvement of the downstream effectors of the PAX3-FOXO1 transcription factor in the oncogenicity of fusion positive rhabdomyosarcomas. In addition, my results help to predict the PAX3-FOXO1 independent mechanisms that could be involved in the development of tumor recurrence when therapies targeting PAX3- FOXO1 will be implemented.
Graduate Researcher During my graduate research I focused on gene regulation at the transcriptional level. Results from my research were highly relevant as they provided new transcription factor targets that are relevant as downstream effectors of these transcription factors in colorectal cancer progression.
Graduate Researcher During my graduate research I focused on gene regulation at the transcriptional level. Results from my research were highly relevant as they provided new transcription factor targets that are relevant as downstream effectors of these transcription factors in colorectal cancer progression.
I had a pathology training in several specialties including Gastroenterology, Gynecology, Endocrinology, Head and Neck and Urology. I performed gross sections, autopsies, and Tissue- Banking. I performed microscopic diagnosis and wrote pathology reports.
Cell engineering, gene knockdown and knockout, xenografts. Gene expression analysis using RNA-seq and microarrays Lentiviral and retroviral transductions. Immunohistochemistry, Immunofluorescence. Digital Image analysis using Nanozoomer, MetaMorph and Image J Tissue Microarray Other skills: Cell culture, cloning, qPCR, Western Blots, ChIP, Live cell imaging.