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jtdr

Journal of Tumor Research

ISSN - 2684-1258

Boron Neutron Capture Therapy

Boron Neutron Capture Therapy (BNCT) is a noninvasive therapeutic modality for treating locally invasive malignant tumors such as primary brain tumors and recurrent head and neck cancer. It is a two-step procedure: first, the patient is injected with a tumor localizing, non-radioactive boron-10 containing drug that has a high propensity to capture slow neutrons. In the second step, the patient is radiated with epithermal neutrons, which after losing energy as they penetrate tissue, are absorbed by the boron-10, and the resulting nuclear capture and fission reactions yield high-energy alpha particles, thereby killing the cancer cells

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