"Coagulation factors, of the proteins annotated to the GO term negative regulation of blood coagulation, annexin A2, apolipoprotein E, and plasminogen there was ambiguous regulation in relation to the preeclamptic state since they were identified as upregulated or downregulated different studies. We speculate that this could be due to heterogeneity in sample sources (Table 1) or maternal response the pathology. Plasminogen isprimarily synthesized in the liver and is cleaved into plasmin at the site of insult by tissue or urokinase plasminogen activators in the early steps of fibrinolysis to the active protease plasmin. OMICS Group International is one of the leading Open Access Publishers which is publishing 700+ peer-reviewed journals with the support of 50,000+ editorial board members as editorial team and aimed to disseminate the scholarly knowledge to the scientific society. OMICS Group also organizing 3000+ International Scientific Conferences and events yearly all over the world with the support of 1000+ Scientific associations worldwide. Citation: Wong F, Cox B (2014) Proteomics Analysis of Preeclampsia, a systematic Review of Maternal and Fetal Compartments. J Proteomics BioinformS10: 001."