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Journal of Genetic Syndromes & Gene Therapy

ISSN - ISSN: 2157-7412

+44 1223 790975

Cystic Fibrosis

CF is a genetic disease that mainly affects the lungs and digestive system, but it can result in fatal complications such as liver disease and diabetes.

The defective gene responsible for CF leads to the creation of thicker, stickier mucus than is usual. This mucus is difficult to cough out of the lungs. This can make breathing difficult and lead to severe lung infections.

The mucus also interferes with pancreatic function by preventing enzymes from properly breaking down food. Digestive problems result, potentially leading to malnutrition.

This thickening of mucus can also cause male infertility by blocking the vas deferens, or the tube that carries the sperm from the testes to the urethra.

CF is serious, with potentially life-threatening consequences. The most common cause of death in people with CF is respiratory failure.

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