Hydroxylation is a chemical process that introduces a hydroxyl group (-OH) into an organic compound. In biochemistry, hydroxylation reactions are often facilitated by enzymes called hydroxylases. Hydroxylation is the first step in the oxidative degradation of organic compounds in air. It is extremely important in detoxification since hydroxylation converts lipophilic compounds into water-soluble (hydrophilic) products that are more readily removed by the kidneys or liver and excreted. Some drugs (for example, steroids) are activated or deactivated by hydroxylation.
Research Article: Drug Designing: Open Access
Research Article: Drug Designing: Open Access
Research Article: Drug Designing: Open Access
Review Article: Drug Designing: Open Access
Review Article: Drug Designing: Open Access
Editorial: Drug Designing: Open Access
Editorial: Drug Designing: Open Access
Commentary: Drug Designing: Open Access
Editorial: Drug Designing: Open Access
Posters & Accepted Abstracts: Journal of Drug Metabolism & Toxicology
Accepted Abstracts: Biochemistry & Pharmacology: Open Access
Scientific Tracks Abstracts: Biochemistry & Pharmacology: Open Access