Children may have a genetic cause of transcription factor deficiency, resulting in trophic hormone hyposecretion. Pituitary tumors, or adenomas, are the most common cause of hypopituitarism in adults, although traumatic brain injury as a cause is being more frequently recognized.

Although there is no cure for hypopituitarism, it is treatable. Successful hormone replacement therapy can enable a patient to live a normal life, feel well and not have the consequences of hormone deficiency.

People with hypopituitarism may have an impaired quality of life. Hypopituitarism is associated with an increased risk of heart disease and strokes as a result of the physical changes that occur in body fat, cholesterol and circulation.Hypopituitarism is a condition in which the pituitary gland (a small gland at the base of the brain) does not produce one or more of its hormones or else not enough of them. ... Some of the problems with hormones, such as with cortisol or thyroid hormone, may require prompt treatment. Others may not be life threatening.