Potato leafroll virus (PLRV) is a member of the genus Polerovirus and family Luteoviridae. The phloem limited positive-sense RNA virus infects potatoes and other members of the family Solanaceae. PLRV was first described by Quanjer et al. in 1916. PLRV is transmitted by aphids, primarily the green peach aphid, Myzus persicae. PLRV is one among the foremost important potato viruses worldwide but particularly devastating in countries with limited resources and management. It is often liable for individual plant yield losses of over 50%. One estimate suggests that PLRV is liable for an annual global yield loss of 20 million tons. Symptoms include chlorosis, necrosis, and leaf curling. PLRV infects members of the family Solanaceae. The most economically important host is Potato.