Staphylococcus aureus is a Gram positive bacterium found as a commensal in humans. Nosocomial S. aureus infections are of major concern because of their serious complications, like bacteremia (blood infection), endocarditis, osteomyelitis (bone infection), skin and soft tissue infections etc. The overall rate of mortality from Staphylococcalbacteremia ranges from 11 to 43 percent, primarily due to the emergence of antibiotic resistant strains. S. aureus infections are now the most common cause for children being hospitalized for surgical drainage of pus, the most common cause of bacteremia in people over 65 years old, and the most serious cause of prosthetic device and intravascular line infection. Risk factors for infection include disruption of mucosal or cutaneous surfaces, introduction of foreign or medical device, surgery, hemodialysis or host immune suppression. A journal is a periodical publication intended to further progress of science, usually by reporting new research. Most journals are highly specialized, although some of the oldest journals publish articles, reviews, editorials, short communications, letters, and scientific papers across a wide range of scientific fields. Journals contain articles that peer reviewed, in an attempt to ensure that articles meet the journal's standards of quality, and scientific validity. Each such journal article becomes part of the permanent scientific record.