Sri Krishnan
Ryerson University, Canada
Keynote: J Neurol Neurophysiol
Many neurological and neuromuscular disease management and screening could benefit from long-term processing and analysis of physiological signals such as EEG, EMG, EOG, PSG, speech, and gait rhythm. The advancements in wearable digital health technologies and the availability of massive storage and computational processing power has made it possible for implementation of advanced mathematical and signal processing techniques for pre-processing tasks such as removal of noise and reduction of interferences/artifacts, extraction of robust features/signatures from physiological signals, and implementing machine learning systems for informed clinical decision making. For example, signal analysis research (SAR) group at Ryerson University has analyzed gait rhythm for automatic classification of Parkinsonā??s, Huntingtonā??s and ALS. We have also processed and analyzed the non-stationary nature of polysomnographic sleep signals in identifying RBD disorders and PLMS. The group is also involved in processing and analyzing sensor information related to EOG and voices in identifying signal features related to diseases such as Parkinsonā??s and sleep related disorders. The challenges associated in these areas are that the signals acquired are non-stationary, produced by non-linear systems, and have variabilities associated with them they could be analyzed to provide rich information in temporal, spectral or spatial domains by using advancements of signal processing and machine learning. The cost effective and patient comfort associated with human factors make them valuable for home-based, telehealth and mobile health based long-term data acquisition and monitoring application. The exponential growth in digital technologies related to sensors and communications (For example, Internet of Things-IoT), and the availability of data and machine learning/AI techniques are all poised to make the field of clinical decision making and patient management even more affordable and ubiquitous. In any of these digital healthcare designs, security and privacy protocols have to be incorporated as part of the design process pipeline. Recent Publications 1. Athavale Y and Krishnan S (2017) Biosignal monitoring using wearables: Observations and opportunities. Biomedical Signal Processing and Control 38:22-33. 2. Wu Y and Krishnan S (2010) Statistical analysis of gait rhythm in patients with Parkinson's disease. IEEE Transactions on Neural Systems and Rehabilitation Engineering, 18(2):150-158. 3. Krishnan S and Athavale Y (2018) Trends in biomedical signal feature extraction. Biomedical Signal Processing and Control 43:41-63.
Sridhar Krishnan has joined Ryerson University, Toronto, Canada in 1999, and currently he is a Professor of Electrical and Computer Engineering, and Co-director of the Institute for Biomedical Engineering, Science and Technology (iBEST). From 2007-2017, he was a Canada Research Chair in Biomedical Signal Analysis. He has published 310 papers in refereed journals and conferences and six of his papers have won best paper awards. He is a Fellow of the Canadian Academy of Engineering.
E-mail: krishnan@ryerson.ca
