Muhammad Rizky Nur Karim, Muhammad Raihan Ramadhan Natadikarta and Ari Sri Wulandari
1Fakhira Sawah Lunto Clinic, Indonesia
Posters & Accepted Abstracts: Clin Exp Ophthalmol
Introduction & Objective: Corneal abrasion and ulcer are common conditions following trauma to the eye. Most patients
seek treatment in the Emergency Room for managing the pain. Topical cycloplegic drugs have been used to help patients
relieve pain in the eye. Despite its common usage, there is no evidence of its efficacy for pain management. This review aimed
to evaluate the use of cycloplegic agents as one kind of pain reliever in corneal abrasion and ulcer cases.
Method: We conduct a computer-based search from several online databases such as Medline, Scopus and Cochrane. We limit
included studies to those written in English and had human participants. Studies were considered eligible if it compared the
effect of cycloplegics with other topical analgesics.
Results: Two studies were eligible for this review and all of them were RCTs. One study reported no significant difference
in VAS pain rating between cycloplegics and placebo. The other study reported that NSAIDs significantly decreased pain
compared to cycloplegics.
Conclusion: This review found that there is still no conclusive evidence about the efficacy of cycloplegics for reducing pain in
corneal abrasions and ulcers. It is advised to further study the benefits of cycloplegics as pain reliever compared to other topical
analgesics.
E-mail: mrizkynkarim@gmail.com
