Emrah Otan
Scientific Tracks Abstracts: J Neurol Neurophysiol
Objective:Liver transplantation is among the outstanding treatment options of end stage liver disease. As a result of the limited organ donation in our country, living donor liver transplantation (LDLT) is performed more frequently. Neurological complications contribute to poor post-operative outcomes following liver transplantation. Our objective is to evaluate the results of neurological complications observed during post-operative intensive care unit follow-up of LDLT patients. Patients and Method: Among the 217 LDLT operations performed between August 2011 and August 2012, neurology consultation was performed for 29 patients (13.36%) due to neurological symptoms. Data of age, sex, primary disease, MELD score, post-operative hospitalisation duration of patients survived were collected retrospectively. Consultation indications and diagnoses were categorised into the groups of acute confussionel state/encephalopathy, epileptic seizures, leucoencephalopathy and focal neurological deficits. Immunsupressive treatment regimens were also examined. Results: Mean age was 44.52±16.24 and there was a male dominence (65.5%, n=19). Acute confussionel state/encephalopathy was the most frequent complication (62.1%, n=18), followed by epileptic seizure (27.6%, n=8), focal neurologic defitics (6.9%, n=2) and leucoencephalopathy (3.4%, n=1). Mortality was significantly high when compared with the overall mortality among patients without neurological complications (65.5% vs. 37.32%, p<0.001). Post-operative hospitalisation duration was significantly extended in the patients with neurological complications group (10.00±5.47 days vs. 29.80±15.04 days, p<0.001). Mortality is significantly high and post-operative hospitalisation duration is significantly extended among LDLT patients with neurological complications.
