Liudmyla D Popova, Oxana Nakonechnaya and Irina Vasylyeva
Kharkiv National Medical University, Ukraine
Posters & Accepted Abstracts: Neurochem Neuropharm
High anxiety is the base not only for depression development but also to impulsive aggression manifestation. We revealed the differences in neurohumoral status in animals with submissive and dominant behavioural types. Hypothalamic pituitary adrenal axis hyperactivity, the increase in noradrenaline and the decrease in serotonin levels in limbicocortical regions were observed in submissive male rats (high anxiety). Due to these results, we studied interrelation between anxiety level and aggressiveness index. The study involved 100 young men aged 18 to 22 years. They were asked to answer Buss-Durkee Hostility Inventory and Spielberger State-Trait Anxiety Inventory. The anxiety level was assessed in points. The aggressiveness index was estimated in a percentage of the maximum level. No correlation between the anxiety level and the aggressiveness index was found in whole group. We divided whole group into three subgroups depending on anxiety level: with high, moderate and low anxiety levels. It should be noted, that the most of men had moderate anxiety level, a few men had low anxiety level. We revealed the existence of high positive correlation between anxiety level and aggression index in men with high anxiety level and negative correlation between these two parameters in men with low anxiety level. In last subgroup correlation was statistically insignificant due to a few men with low anxiety level. In men with moderate anxiety level no correlation between anxiety level and aggression index was observed. This interrelation may be taken into account in anxiety treatment and in the prevention of impulsive aggression manifestation.
Liudmyla D Popova has PhD degree, degree of Doctor of Biology Sciences, and the title of Biochemistry Department Professor. She is presently Biochemistry Department Professor in Kharkiv National Medical University, Ukraine, Oxana.
Email: popova_ld@ukr.net
