Jianrong Yue
Shenzhen Third People�s Hospital, China
Posters-Accepted Abstracts: Pediat Therapeut
Hand-Foot-Mouth-Disease (HFMD) caused by EV71 infection is a common childhood disease in recent years in Shenzhen. While most cases are self-limited with mainly skin rash, severe cases are presented in a small proportion of EV71 infected subjects. Clinically, these cases manifested with brain stem encephalitis and even death. Therefore, early diagnosis of severe cases is critical for successful treatment and consequently to reduce mortality. During 2012 to 2014, over than 2310 cases of EV71 HFMD have been hospitalized in our hospital. Among them, 267 cases were diagnosed as severe HFMD.The treatment success rate is significantly higher than the average of whole country. The clinical manifestations including skin rash, fever, vital signs, and consciousness were the key point for intensive monitoring. Clinically, continued high fever (>39oC), increased blood pressure (systolic blood pressure >118 MMHG), small and hidden skin rash, facial or lip Angle jitter were important clinical manifestations for early diagnosis and/or prediction of severe cases, of which required early intervention.
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