Azadeh Mottaghi, Narges Zaeemzadeh and Saeideh Ziaei
Iran University of Medical Sciences, Iran
Tarbiat Modares University, Iran
Posters & Accepted Abstracts: Reprod Syst Sex Disord
Polycystic ovary syndrome (PCOS), is the most common endocrine disorder among women in reproductive age. This study aimed to determine the relationship between MetS (metabolic syndrome) and the nutritional status of patients with PCOS and serum androgen levels in four different subtypes of PCOS. The study subjects were compared with (PCOS women in reproductive age (18-40 years old)) with the matched control group. Case group, was divided to 4 subgroups based on diagnostic Rotterdam criteria. Clinical, hormonal and biochemical assessments was done and food frequency questionnaire was completed for all subjects. Diagnosis of MetS, was carried out based on NCEP ATP III criteria. A statistically significant difference in hormonal factors (androgenic components) and some nutritional components was observed among the PCOS subgroups with each other and with the control group (P<0.05). The prevalence of MetS among PCOS subgroups with each other and with the control group, has a statistically significant difference (P<0.05). A significant association was found between some of the nutritional components with some of the MetS components in all subgroups of PCOS and the control group (P<0.05). Serum total testosterone level was significantly higher in PCOS women with the MetS than those with no MetS (P<0.05). A significant association was found between some of the nutritional components with androgenic components level in all subgroups of PCOS and the control group (P<0.05). The majority of investigated nutritional components in PCOS women with and without MetS, have shown a significant difference (P<0.05). Unfavorable nutritional condition increase risk of MetS in women with PCOS, via the influence on the MetS components and androgenic components.
