Fragment based drug design is identification of fragments or components of low molecular weight or lead compounds, which can bind with weak affinity to the target site. Fragment based discovery involved finding such weakly binding fragments and grow them or combine them in order to create lead components with higher affinity or selectivity to bimolecular target site. These techniques achieved credible success in drug development.
Related Journals of Fragment based Drug Designing
Advances in Pharmacoepidemiology & Drug Safety, Molecular Enzymology and Drug Targets, Advances in Antiviral Drug Design, Drug Design Reviews Online , Frontiers in Drug Design and Discovery and International Journal of Computational Biology and Drug Design and Chemical Biology & Drug Design.