Metabolic engineering has the potential to produce from simple,readily available, inexpensive starting materials a large number of chemicals that are currently derived from nonrenewable resources or limited natural resources.It was used for the production of chemicals from renewable resources.These technologies include gene expression, artificial evolution, protein design and engineering,high throughput screening,mutagenesis and selection ,fermentation development and product recovery.
Metabolic engineering has the potential to produce from simple, readily available, inexpensive starting materials a large number of chemicals that are currently derived from nonrenewable resources or limited natural resources. Microbial production of natural products has been achieved by transferring product-specific enzymes or entire metabolic pathways from rare or genetically intractable organisms to those that can be readily engineered, and production of unnatural specialty chemicals, bulk chemicals, and fuels has been enabled by combining enzymes or pathways from different hosts into a single microorganism and by engineering enzymes to have new function. Whereas existing production routes use well-known, safe, industrial microorganisms, future production schemes may include designer cells that are tailor-made for the desired chemical and production process. In any future, metabolic engineering will soon rival and potentially eclipse synthetic organic chemistry.
Related Journals of Metabolic Pathway Engineering
Immunology, Genetic Disorders & Genetic Reports, Hereditary Genetics: Current Research, Biological Systems : Open Access, Metabolic Engineering, Enzymes, Coenzymes & Metabolic Pathways, Metabolic Engineering Communications.
