Oxidative stress is essentially an imbalance between the production of free radicals and the ability of the body to counteract or detoxify their harmful effects through neutralization by antioxidants. Oxidative stress is likely to be involved in age-related development of cancer. The reactive species produced in oxidative stress can cause direct damage to the DNA and are therefore mutagenic.
Oxidative stress has been defined as harmful because oxygen free radicals attack biological molecules such as lipids, proteins, and DNA. However, oxidative stress also has a useful role in physiologic adaptation and in the regulation of intracellular signal transduction. Therefore, a more useful definition of oxidative stress may be “a state where oxidative forces exceed the antioxidant systems due to loss of the balance between them.”
Related Journals of Oxidative Stress
Journal of Biomedical Engineering and Medical Devices, Traumatic Stress Disorders & Treatment, Journal of Environmental Radioactivity, European Journal of Obstetrics & Gynecology and Reproductive Biology, Journal of Biomedical Science, European Journal of Internal Medicine, Journal of Toxicology and Environmental Health-part A.
